Data Structures & Algorithms

Q1. (5 pts):  Write the line of code that would install the package ggplot2 in R.

Q2. (10 pts):  Compare and contrast VCF and GFF files.

Q3. (10 pts):  Compare & Contrast FASTA and FASTQ files.

Q4. (5 pts):  What are comment lines in an algorithm?  When should they be used?

Q5. (15 pts):  What are SAM, BAM, and BAI files?  What are the differences between them files?  How are they generated?

Q6. (20 pts):  For a given algorithm, how will BigO change if the algorithm is run on different hardware (e.g. a faster processor)?  How will it change if a larger data set is run through the algorithm?  Explain.

Q7. (25 pts):  Using pseudocode, describe an algorithm that sums the values between 1 and N for a given value of N.  What do you think the BigO will be for this algorithm and why?

Q8. (10 pts):  Many bioinformatics data file formats utilize plain text as a storage format. 

  • List 5 bioinformatics data formats that are in fact simply structured plain text
  • List 3 different editors that would work well for editing Plain Text (Hint:  MS Word is NOT good for editing plain text!).

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