EP 170 – Cardiac Research Trials
Like anything in Medicine, practice is dictated by evidence obtained by research. This week’s assignment requires you to research the trials listed below (format as you see fit) and correlate these outcomes to present day practice.
Utilizing your findings, provide detailed (supported) responses to the following:
- How does this research impact the care provided to today’s cardiac and heart failure patients?
- What was the significance of the DAVID trial outcome and how has the EP community modified patient care based on this?
- Based on the research findings, what is “best practice” for the treatment of sudden cardiac death? Support your response with additional resources.
All of your work must be referenced appropriately in APA format
| Trial | Purpose of Study | Research Summary | # of Participants | Research Study Outcome |
| Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) | ||||
| Antiarrhythmics Vs. implantable defibrillators (AVID) | ||||
| Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) | ||||
| Multicenter Automatic Defibrillator Implantation Trial I, II (MADIT I – MADIT II) | ||||
| Defibrillation in Acute Myocardial Infarction trial (DINAMIT) | ||||
| Multicenter Unsustained Tachycardia Trial (MUSTT) | ||||
| Defibrillators in Non-Ischemic CMO Treatment Evaluation (DEFINITE) | ||||
| Dual Chamber and VVI Implantable Defibrillator (DAVID) | ||||
| Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic HF on Mortality (DANISH) | ||||
| Coronary Artery Bypass Graft (CABG) Patch |
References
